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To expand the limits of transdermal drug delivery, will affect developers using energy sources such as ultrasound, heat and electrical power to the active transport through the skin. Another approach is the modification or removal of the surface layers of the skin, a group of technologies collectively microporation, alone or in conjunction with the energy-enabled devices, the size and nature of the drug molecules is able to expand the transdermal delivery can be used. These techniques can increase the upper molecular size limit dramatically, opening up a multitude of opportunities for transdermal administration..Doctors Without Borders welcomes the efforts of UNITAID. Middle of 2010 that the pool was given the thumbs, patentee of terminology of general support to businesses and formal license commitments need to move, their policy director, Michelle Childs , said in a statement, by to the news agency .